protein

ACAT2 Protein, Human (Trx-His)

HY-P71041

10 μg;50 μg

170;510 USD

ACAT2 Protein, Human (Trx-His)

proteins

E. coli

10 μg;50 μg

170;510 USD

ACAT2, Human (Trx-His) is the major ACAT enzyme in human hepatocytes. ACAT2, Human is an important regulator of susceptibility to the development of atherosclerosis.

Human

ACAT2 is the major ACAT enzyme in human hepatocytes. Currently, two ACAT isozymes, ACAT1 and ACAT2, have been identified in humans and in animals. ACAT2 expression predominantly in the liver and intestine. ACAT2 is the major isoenzyme in monkey and mouse hepatocytes. ACAT1 is the major isoform in human hepatocytes. ACAT2 is identified as an important regulator of susceptibility to the development of atherosclerosis. Studies in mouse models of atherosclerosis showed reduced amounts of atherosclerosis when ACAT2 was deficient [1] [2] .

Acetyl-CoA acetyltransferase cytosolic; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; ACTL; ACAT2

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, 10% Glycerol, pH 8.0.

Shipping with dry ice.