protein

STX7 Protein, Human (HEK293, His)

HY-P71024

10 μg;50 μg

105;300 USD

STX7 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

105;300 USD

The STX7 protein plays a key role in protein trafficking and membrane fusion events. It guides proteins from the plasma membrane to early endosomes, facilitates homotypic fusion of endocytic organelles, and mediates transport from early endosomes to late endosomes and lysosomes. STX7 Protein, Human (HEK293, His) is the recombinant human-derived STX7 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of STX7 Protein, Human (HEK293, His) is 237 a.a., with molecular weight of 31-36 kDa.

Human

STX7 Protein emerges as a pivotal player in cellular processes governing protein trafficking and membrane fusion events. It is implicated in the trafficking of proteins from the plasma membrane to the early endosome (EE) and contributes to the homotypic fusion of endocytic organelles. Additionally, STX7 mediates endocytic trafficking from early endosomes to late endosomes and lysosomes, emphasizing its role in the dynamic regulation of endosomal compartments. By forming a SNARE complex with VTI1B, STX8, and VAMP8, STX7 plays a crucial role in the homotypic fusion of late endosomes. It is also a component of the SNARE complex, along with STX8, VAMP7, and VTI1B, essential for the heterotypic fusion of late endosomes with lysosomes. Interactions with VPS11, VPS16, VPS18, VPS33A, and TPC1 underscore the intricate network of associations, revealing the multifaceted involvement of STX7 in coordinating membrane fusion events and protein trafficking within the endocytic pathway. Investigating the detailed mechanisms underlying STX7's functions could provide valuable insights into its regulatory role in cellular membrane dynamics.

Syntaxin-7; STX7; syntaxin 7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US;may vary elsewhere.