protein

PRAP1 Protein, Human (HEK293, His)

HY-P71004

10 μg;50 μg

120;360 USD

PRAP1 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

120;360 USD

Proline-rich acidic protein 1 (PRAP1) is a lipid-binding protein which promotes lipid absorption; negatively regulates the apoptotic process; gets involved in p53/TP53-dependent cell survival after DNA damage; causes cell cycle arrest; maintains normal growth homeostasis in epithelial cells and suppress mitotic spindle assembly checkpoint in hepatocellular carcinomas. PRAP1 Protein, Human (HEK293, His) is the recombinant human-derived PRAP1 protein, expressed by HEK293 , with C-6*His labeled tag.

Human

Proline-rich acidic protein 1 (PRAP1) is a lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. PRAP1 also negatively regulates the apoptotic process , gets involved in p53/TP53-dependent cell survival after DNA damage and may cause cell cycle arrest. PRAP1 may play an important role in maintaining normal growth homeostasis in epithelial cells and may down-regulate the expression of MAD1L1, exerting a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas [1] [2] [3] .

Proline-Rich Acidic Protein 1; Epididymis Tissue Protein Li 178; Uterine-Specific Proline-Rich Acidic Protein; PRAP1; UPA

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.