protein

ZWINT/ZW10 interactor Protein, Human (His)

HY-P71000

5 μg;10 μg

65;110 USD

ZWINT/ZW10 interactor Protein, Human (His)

proteins

E. coli

5 μg;10 μg

65;110 USD

ZW10 interactor (ZWINT) is clearly involved in kinetochore function. ZWINT interacts with ZW10, a kinetochore protein, possibly regulating the association between ZW10 and kinetochores. ZWINT is required for kinetochore formation and spindle checkpoint activity and remains detectable on the kinetochore until late anaphase. ZWINT has a uniform distribution in the cytoplasm of interphase cells. ZWINT/ZW10 interactor Protein, Human (His) is the recombinant human-derived ZWINT/ZW10 interactor protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZWINT/ZW10 interactor Protein, Human (His) is 277 a.a., with molecular weight of ~35 kDa.

Human

ZW10 interactor (ZWINT) is clearly involved in kinetochore function. ZWINT interacts with ZW10, a kinetochore protein, possibly regulating the association between ZW10 and kinetochores. ZWINT is part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. ZWINT localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. ZWINT has a uniform distribution in the cytoplasm of interphase cells [1] [2] [3] [4] .

ZW10 Interactor; ZW10-Interacting Protein 1; Zwint-1; ZWINT

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.