protein

SUMO1 Protein, Human (His)

HY-P70997

10 μg;50 μg

35;98 USD

SUMO1 Protein, Human (His)

proteins

E. coli

10 μg;50 μg

35;98 USD

SUMO1 Protein is a member of the SUMO (small ubiquitin-like modifier) protein family. SUMO1 binds to target proteins as part of a post-translational modification system. It is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 also regulates the function of several proteins via non-covalent interactions. SUMO1 Protein, Human (His) is the recombinant human-derived SUMO1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SUMO1 Protein, Human (His) is 101 a.a., with molecular weight of 17-19 kDa.

Human

Small ubiquitin-related modifier 1 (SUMO1) is an ubiquitin-like protein that is a member of the SUMO protein family. SUMO1 binds to target proteins as part of a post-translational modification system. It is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. And it is not active until the last four amino acids of the carboxy-terminus have been cleaved off. SUMO1 also regulates the function of several proteins via non-covalent interactions involving the hydrophobic patch in the target protein identified as SUMO Binding or Interacting Motif (SBM/SIM). SUMO1 hinders α-Synuclein fibrillation by inducing structural compaction. SUMO1 acts as a signal for proteasomal degradation of modified proteins, and regulates a network of genes involved in palate development. It is also critical for post-infarction heart repair and that deletion of the SUMO1 gene aggravated myocardial injury after myocardial infarction (MI) [1] [2] [3] [4] .

Small Ubiquitin-Related Modifier 1; SUMO-1; GAP-Modifying Protein 1; GMP1; SMT3 Homolog 3; Sentrin; Ubiquitin-Homology Domain Protein PIC1; Ubiquitin-Like Protein SMT3C; Smt3C; Ubiquitin-Like Protein UBL1; SUMO1; SMT3C; SMT3H3; UBL1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.5 .

Room temperature in continental US; may vary elsewhere.