protein

WIF-1 Protein, Human (HEK293, His)

HY-P70982

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

40;70;205;360;700;1200;1750 USD

WIF-1 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

40;70;205;360;700;1200;1750 USD

WIF-1 protein critically binds to WNT protein, inhibits its activity and regulates the WNT signaling pathway. In addition to its inhibitory role, WIF-1 may also contribute to mesoderm segmentation, implicating its role in embryonic development. WIF-1 Protein, Human (HEK293, His) is the recombinant human-derived WIF-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of WIF-1 Protein, Human (HEK293, His) is 351 a.a., with molecular weight of 42-48 kDa.

Human

The WIF-1 protein plays a crucial role as it binds to WNT proteins, effectively inhibiting their activities. This interaction suggests a pivotal regulatory function in WNT signaling pathways. Beyond its inhibitory role, WIF-1 may also be involved in mesoderm segmentation, hinting at its potential contributions to embryonic development. Furthermore, WIF-1 interacts with MYOC, indicating a possible association with additional cellular processes or signaling cascades. The multifaceted interactions of WIF-1 underscore its importance in modulating WNT-mediated activities and its potential involvement in broader developmental and cellular events.

Wnt Inhibitory Factor 1; WIF-1; WIF1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 0.5% CHAPS, pH 4.0 or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4 or 20 mM Glycine-HCl, 10% Sucrose, 5% Mannitol , 0.05% Tween80, pH 3.5.

Room temperature in continental US; may vary elsewhere.