protein

Fetuin B Protein, Human (HEK293, His)

HY-P70930

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;50;140;240;770;1400 USD

Fetuin B Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;50;140;240;770;1400 USD

Fetuin B, a vital protease inhibitor, plays a crucial role in egg fertilization by preventing premature zona pellucida hardening before fertilization. Its primary function involves inhibiting the protease activity of ASTL, preventing ZP2 cleavage and zona pellucida hardening. Fetuin B's regulatory role emphasizes its significance in creating optimal conditions for successful fertilization and subsequent embryonic development. Fetuin B Protein, Human (HEK293, His) is the recombinant human-derived Fetuin B protein, expressed by HEK293 , with C-6*His labeled tag.

Human

Fetuin B emerges as a crucial protease inhibitor essential for egg fertilization. Its primary role is to prevent premature hardening of the zona pellucida before fertilization, a critical process for successful embryonic development. This function is likely mediated through the inhibition of the protease activity of ASTL, a key enzyme responsible for cleaving ZP2 and triggering the hardening of the zona pellucida. Fetuin B's regulatory role in this process highlights its significance in facilitating the proper conditions for successful fertilization and subsequent embryonic development.

Fetuin-B; 16G2; Fetuin-Like Protein IRL685; Gugu; FETUB

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2 or PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.