TPO/Thrombopoietin Protein, Mouse (CHO) | MedChem Express LLC HY-P7088 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

TPO/Thrombopoietin Protein, Mouse (CHO)

catalog :

HY-P7088

quantity :

10 μg;50 μg;100 μg

price :

70;200;340 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7088

Product Name :

TPO/Thrombopoietin Protein, Mouse (CHO)

Product Type :

proteins

Host Species :

CHO

Size :

10 μg;50 μg;100 μg

List Price :

70;200;340 USD

list of Pubmed id :

375588551

Product Description :

TPO Protein, Mouse (CHO) is a hematopoietic factor that controls platelet production.

SpeciesSummary :

Mouse

Background :

Recombinant thrombopoietin reduces radiation- and chemotherapy-induced thrombocytopenia, enhances platelet recovery after bone marrow transplantation and increases the number of megakaryocyte precursor cells in stem cell harvests. Injection of thrombopoietin into animals stimulates the number, size and ploidy of bone marrow megakaryocytes and increases the platelet count up to ten-fold [1] . Superphysiological amounts of Thrombopoietin/TPO (>100 ng/mL) are able to directly activate platelet aggregation in vitro . Thrombopoietin/TPO also has significant effects on platelet adhesion under flow. Low Thrombopoietin/TPO concentrations (001-1 ng/mL) accelerate firm platelet adhesion to von Willebrand factor and prevent de-attachment at higher flow rates [2] .

ALTnames :

rMuTPO; TPO

Purity :

Greater than 95% as determined by reducing SDS-PAGE

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage