protein

GALNT7 Protein, Human (HEK293, His)

HY-P70867

10 μg;50 μg

155;430 USD

GALNT7 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

155;430 USD

The GALNT7 protein serves as an indispensable glycopeptidyl transferase for O-linked oligosaccharide biosynthesis. Its enzymatic activity involves catalyzing the transfer of N-acetyl-D-galactosamine residues to pre-existing glycosylated peptides. GALNT7 Protein, Human (HEK293, His) is the recombinant human-derived GALNT7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GALNT7 Protein, Human (HEK293, His) is 628 a.a., with molecular weight of 65-80 kDa.

Human

GALNT7 is a glycopeptide transferase that plays a crucial role in O-linked oligosaccharide biosynthesis. Unlike other members of its protein family, GALNT7 does not act as a peptide transferase that directly transfers N-acetyl-D-galactosamine (GalNAc) onto a serine or threonine residue on the protein receptor. Instead, it catalyzes the transfer of GalNAc to an already glycosylated peptide, requiring the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. While GALNT7 primarily functions in O-linked glycosylation, some peptide transferase activity cannot be entirely excluded, and the identification of its appropriate peptide substrate remains a subject of ongoing investigation.

PolypeptideGalNAc-transferase7; Protein-UDP acetylgalactosaminyltransferase7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7; GALNT7.

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0.

Shipping with dry ice.