protein

Follistatin-like 1/FSTL1 Protein, Mouse (HEK293, His)

HY-P70859

10 μg;50 μg;100 μg;500 μg

60;160;280;950 USD

Follistatin-like 1/FSTL1 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg;100 μg;500 μg

60;160;280;950 USD

Follistatin-like 1 (FSTL1) is a secreted glycoprotein that plays multiple roles in angiogenesis, immune regulation, and cell differentiation. It positively affects the development of the central nervous system, skeletal system, lungs and ureters. Follistatin-like 1/FSTL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Follistatin-like 1/FSTL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Follistatin-like 1/FSTL1 Protein, Mouse (HEK293, His) is 288 a.a., with molecular weight of 41-58 kDa.

Mouse

Follistatin-like 1 (FSTL1) is a secreted glycoprotein with diverse roles in various physiological processes, including angiogenesis, immune response regulation, and cell proliferation and differentiation. It actively participates in the development of the central nervous system, skeletal system, lungs, and ureter. FSTL1 exerts its influence on endothelial cells by promoting survival, migration, and differentiation into network structures through an AKT-dependent mechanism, while also supporting the survival of cardiac myocytes. The glycoprotein initiates signaling cascades by activating different cell surface receptors, including DIP2A, TLR4, and BMP receptors. FSTL1 forms homodimers and interacts with SCN10A, DIP2A (acting as a potential cell surface receptor), BMP4, and CD14, with the latter interaction promoting TLR4-mediated signaling cascades. These interactions highlight the multifaceted nature of FSTL1 in orchestrating various cellular functions and signaling pathways.

Follistatin-related protein 1; Follistatin-like protein 1; TGF-beta-inducible protein TSC-36; Fstl1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.