protein

TSLPR Protein, Mouse (HEK293, Fc)

HY-P70823

10 μg;50 μg

150;420 USD

TSLPR Protein, Mouse (HEK293, Fc)

proteins

HEK293

10 μg;50 μg

150;420 USD

Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for TSLP. Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway. The expression of Crlf2 usually upregulates and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL) [1] [2] . TSLPR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TSLPR protein, expressed by HEK293 , with C-hFc labeled tag.

Mouse

Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for thymic stromal lymphopoietin (TSLP). Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway (STAT3 and STAT5). Crlf2 usually upregulated and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL) [1] [2] .

CRL2; CRLF2; CRL2 cytokine receptor; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; Thymic stromal lymphopoietin protein receptor; Thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.