IL-7 Protein, Mouse (CHO) | MedChem Express LLC HY-P7082 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

IL-7 Protein, Mouse (CHO)

catalog :

HY-P7082

quantity :

10 μg;50 μg

price :

115;325 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7082

Product Name :

IL-7 Protein, Mouse (CHO)

Product Type :

proteins

Host Species :

CHO

Size :

10 μg;50 μg

List Price :

115;325 USD

list of Pubmed id :

375588544

Product Description :

IL-7 Protein, Mouse (CHO) is constitutively produced by stromal cells from the bone marrow and thymus, plays a crucial role in B cell lymphopoiesis and in T cell homeostasis.

SpeciesSummary :

Mouse

Background :

Interleukin-7 (IL-7) is a nonredundant cytokine produced by nonlymphoid cells that is essential for T-cell development in humans and mice and B-cell development in mice. IL-7 contributes to the maintenance of the size and subset composition of the peripheral T-cell pool by providing growth and survival signals through the IL-7 receptor. The IL-7 receptor has a private α-chain and shares the common γ-chain (γ c ) with other common cytokine receptor users, such as IL-2, IL-4, IL-15, and IL-21. IL-7 together with these cytokines regulates the expansion and contraction of adaptive immune responses and potentially the memory response to a given antigen. IL-7 modulates memory CD8 + T cells in response to a virus infection and, given in conjunction with adoptive transfer of T cells after herpes simplex virus type 1 infection, improves virus clearance [1] .

ALTnames :

rMuIL-7; LP-1; pre-B cell factor

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage