protein

PVR/CD155 Protein, Human (HEK293, His)

HY-P70807

10 μg;50 μg

107;300 USD

PVR/CD155 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

107;300 USD

PVR/CD155 Protein, Human (HEK293, His) is a recombinant Human PVR expressed in HEK 293 cells with a His tag at the N-terminus. PVR, Human plays a role in cancer cell invasion and migration [1] [2] .

Human

PVR/CD155, also known as the human poliovirus receptor (PVR) is a member of the subfamily of immunoglobulin (Ig)-like molecules composed of an N-terminal variable-like, followed by two constant-like extracellular domains, a single transmembrane region and a cytoplasmic tail of variable length. CD155 binds the extracellular matrix protein vitronectin thereby mediating cell to matrix contacts. The cytoplasmic tail of CD155 interacts with the μ1B subunit of the clathrin adaptor complex resulting in directed transport of CD155 in polarized epithelial cells [1] [2] .

Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Shipping with dry ice.