protein

IL-21 Protein, Mouse (129a.a)

HY-P7078

2 μg;10 μg;50 μg;100 μg

58;150;420;680 USD

IL-21 Protein, Mouse (129a.a)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

58;150;420;680 USD

375588539

IL-21 Protein, Mouse (129a.a) is a regulatory cytokine thought to play a role in the transition between innate and adaptive immunity.

Mouse

Interleukin 21 (IL-21) is a novel type I cytokine that is significantly homologous to IL-2, IL-4 and IL-15. Its receptor complex contains gammac chain which is also a component of receptors for IL-2, IL-4, IL-7, IL-9 and IL-15, so there may be overlapping or relevancies in their biological functions. IL-21 is capable of co-stimulating mature T cells, B cells, NK cells, and of stimulating CD16 expression on the surface of NK cells to induce ADCC in innate immune response. It can also strengthen the anti-tumor effect of the cellular immunity, especially via enhancing the activities of NK and antigen specific CTL cells. Thus, IL-21 is a potential useful therapeutic molecule for immunotherapy of malignancies, by eliciting innate and adaptive anti-tumor responses in tumor-bearing hosts [1]

rMuIL-21; Za11; IL21

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS.

Room temperature in continental US; may vary elsewhere.