protein

IL-2 Protein, Mouse

HY-P7077

2 μg;5 μg;10 μg;50 μg;100 μg

50;88;140;340;578 USD

IL-2 Protein, Mouse

proteins

E. coli

2 μg;5 μg;10 μg;50 μg;100 μg

50;88;140;340;578 USD

375588538

IL-2 Protein, Mouse is an immunomodulatory cytokine with widely varying functions including promotion of apoptosis, proliferation and survival of lymphocytes.

Mouse

Interleukin-2 (IL-2) is a multi-faceted cytokine, known for promoting proliferation, survival, and cell death depending on the cell type and state. For example, IL-2 facilitates cell death only in activated T cells when antigen and IL-2 are abundant. The availability of IL-2 clearly impacts this process. IL-2 is retained in blood vessels by heparan sulfate, and that biologically active IL-2 is released from vessel tissue by heparanase. The morphologic changes and rapid cell death induced by dimeric IL-2 imply that cell death is mediated by disruption of membrane permeability and subsequent necrosis. IL-2 has a direct and unexpectedly broad influence on cellular homeostatic mechanisms in both immune and non-immune systems [1] .

rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM Sodium Citrate, 0.2% Tween 80, pH 3.0 or 10 mM Sodium Citrate, pH 4.0.

Room temperature in continental US; may vary elsewhere.