protein

IL-4R alpha/CD124 Protein, Human (HEK293, His)

HY-P70710

10 μg;50 μg

115;320 USD

IL-4R alpha/CD124 Protein, Human (HEK293, His)

Protein

HEK293

10 μg;50 μg

115;320 USD

IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-H232) is produced in HEK293 cells with a C-Terminal His-tag.