protein

IGF-I/IGF-1 Protein, Mouse

HY-P7070

2 μg;10 μg;50 μg;100 μg

35;90;190;350 USD

IGF-I/IGF-1 Protein, Mouse

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;90;190;350 USD

375588528

IGF-I/IGF-1 Protein, Mouse is a mitogenic cytokine.

Mouse

Insulin-like growth factor (IGF) system has been shown to modulate growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. Insulin-like Growth factor-1 (IGF-I) is produced by osteoblasts, and its mitogenic effects are mediated by their binding to the IGF plasma membrane receptors. The IGF type 1 receptor binding to both IGF-I and IGF-II, is thought to be the predominate receptor involved in mediating the effects of these growth factors in most cell types, including osteoblasts [1] . Insulin-like growth factor-1 (IGF-1) is a neurotrophic factor capable of mediating neuroprotective and neuroplasticity mechanisms. Targeted overexpression of IGF-1 enhances the generation of hippocampal newborn neurons in brain-injured mice [2] .

rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.