protein

CD64 Protein, Human (HEK293, His)

HY-P70669

10 μg;50 μg

79;220 USD

CD64 Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

79;220 USD

CD64 protein, a high affinity receptor, mediates IgG effector functions, triggering antibody-dependent cellular cytotoxicity (ADCC). It interacts with IGHG1 and forms a signaling complex with FCERG1, contributing to immune responses. CD64 also interacts with FLNA, EPB41L2, LAT, PPL, HCK, and LYN to prevent degradation of FCGR1A and regulate immune function. CD64 Protein, Human (HEK293, His) is the recombinant human-derived CD64 protein, expressed by HEK293 , with C-6*His labeled tag.

Human

CD64 protein is a high affinity receptor for the Fc region of immunoglobulins gamma. It plays a role in both innate and adaptive immune responses. CD64 mediates IgG effector functions on monocytes, triggering antibody-dependent cellular cytotoxicity (ADCC) against virus-infected cells. It interacts with IGHG1 and forms a functional signaling complex with FCERG1. CD64 also interacts with FLNA, preventing degradation of FCGR1A. Additionally, it interacts with EPB41L2, LAT, PPL, HCK, and LYN, contributing to its diverse functions in immune regulation.

Ig gamma-4 chain C region,IgG4 Fc

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.