protein

Irisin Protein, Human/Mouse/Rat (HEK293, Fc)

HY-P70665

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

35;78;220;375;750;1200;1700 USD

Irisin Protein, Human/Mouse/Rat (HEK293, Fc)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

35;78;220;375;750;1200;1700 USD

Irisin is a hormone derived from the FNDC5 gene that promotes energy expenditure via thermogenesis. Irisin Protein, Human/Mouse/Rat (HEK293, Fc) is the recombinant human-derived Irisin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Irisin Protein, Human/Mouse/Rat (HEK293, Fc) is 112 a.a., with molecular weight of 42-60 kDa.

Rat;Mouse;Human

Irisin is a hormone found to be derived from the fibronectin type III domain (FNDC5) gene, which is primarily released from skeletal muscle following exercise or exposure to cold. Irisin is primarily secreted by muscle and increases with exercise. In particular, irisin has been shown to have beneficial effects on adipose tissue, brain, and bone [1] . Recombinant human/mouse/rat irisin protein (20-200 ng/ml; 24 h) had no effect on E-selectin expression at low concentrations. When HUVECs were treated with high concentrations of irisin (200 ng/ml), soluble E-selectin concentrations were similar to levels detected in controls treated with regular growth medium [2] .

Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Irisin; FNDC5

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80 or PBS, pH 7.4, 8% trehalose or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.