protein

Animal-Free IL-2 Protein, Mouse (His)

HY-P70646AF

2 μg;10 μg;50 μg

65;180;500 USD

Animal-Free IL-2 Protein, Mouse (His)

proteins

E. coli

2 μg;10 μg;50 μg

65;180;500 USD

IL-2 Protein is usually produces by antigen-activated CD4+ T cells, CD8+ T cells, NK cells and NKT cells. IL-2 Protein is involved in signaling pathways including JAK/STAT, inosine phosphate 3-kinase /PI3K, and mitogen-activated protein kinase /MAPK. Animal-Free IL-2 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-2 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-2 Protein, Mouse (His) is 149 a.a., with molecular weight of ~18.2 kDa.This product is for cell culture use only.

Mouse

IL-2 is a receptor cytokine produced by activated CD4-positive helper T cells and plays its role by activating JAK/STAT, inosine phosphate 3-kinase /PI3K and mitogen-activated protein kinase /MAPK. IL-2 binds to receptor complexes consisting of high affinity trimers IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or low affinity dimers IL-2R (IL2RB and IL2RG). IL-2 can increase the cytolytic activity of NK cells. Promote strong proliferation of activated B cells and immunoglobulin production. IL-2 is involved in differentiation and homeostasis of effector T cell subsets, including Th1, Th2, Th17, and memory CD8-positive T cells. IL-2 synthesis is strictly regulated by TCR and CD28 signaling at the mRNA level. It mediates the activation induced cell death (AICD) process. IL-2 can be used in the research of cancer immunotherapy [1] [2] [3] [4] [5] [6] .

rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a solution containing 1X PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.