protein

GMP TPO/Thrombopoietin Protein, Human (HEK293, His)

HY-P70637G

50 μg

450 USD

GMP TPO/Thrombopoietin Protein, Human (HEK293, His)

proteins

HEK293

50 μg

450 USD

TPO/Thrombopoietin Protein, a lineage-specific cytokine, significantly influences megakaryocyte proliferation and maturation, particularly in late developmental stages from committed progenitor cells. It emerges as a potential major physiological regulator, underscoring its crucial role in the intricate orchestration of circulating platelets and emphasizing its importance in megakaryocyte biology and platelet formation. GMP TPO/Thrombopoietin Protein, Human (HEK293, His) is the recombinant human-derived TPO/Thrombopoietin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMP TPO/Thrombopoietin Protein, Human (HEK293, His) is 332 a.a., with molecular weight of 70-90 kDa.

Human

Thrombopoietin (TPO), a lineage-specific cytokine, exerts a pivotal influence on the proliferation and maturation of megakaryocytes, particularly at the late stages of their development from committed progenitor cells. Notably, TPO emerges as a potential major physiological regulator in the intricate orchestration of circulating platelets, underscoring its crucial role in megakaryocyte biology and platelet formation.

Thrombopoietin; C-mpl ligand; MGDF; THPO

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.