protein

IL-2R alpha/CD25 Protein, Human (HEK293, C-His)

HY-P70628

10 μg;50 μg

107;300 USD

IL-2R alpha/CD25 Protein, Human (HEK293, C-His)

proteins

HEK293

10 μg;50 μg

107;300 USD

IL-2R alpha protein is the receptor for interleukin 2 and plays a crucial role in immune tolerance by regulating the activity of regulatory T cells (TREG). These TREGs are responsible for inhibiting the activation and expansion of autoreactive T cells.IL-2R alpha/CD25 Protein, Human (HEK293, C-His) is the recombinant human-derived IL-2R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

Human

IL-2R alpha, a receptor for interleukin-2, plays a pivotal role in the regulation of immune tolerance by modulating the activity of regulatory T cells (TREGs). TREGs function to suppress the activation and expansion of autoreactive T-cells, contributing to immune homeostasis. The receptor exists in three distinct forms: a high-affinity dimer, an intermediate-affinity monomer (beta subunit), and a low-affinity monomer (alpha subunit). Both high and intermediate affinity forms can associate with a gamma subunit, highlighting the multifaceted nature of IL-2R in mediating immune responses.

IL-2R alpha; IL-2RA; Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 10 mM HEPES, 50 mM NaCl, pH 7.2.

Room temperature in continental US;may vary elsewhere.