protein

Serpin F1 Protein, Mouse (375a.a)

HY-P70584

10 μg;50 μg

100;280 USD

Serpin F1 Protein, Mouse (375a.a)

proteins

E. coli

10 μg;50 μg

100;280 USD

Serpin F1 is a neurotrophin that significantly induces extensive neuronal differentiation of retinoblastoma cells and exhibits potent anti-angiogenic effects.Its unique conformation lacks the S (stress) to R (relaxation) transition typical of active serpins, resulting in a lack of serpin activity.Serpin F1 Protein, Mouse is the recombinant mouse-derived Serpin F1 protein, expressed by E.coli , with tag free.

Mouse

Serpin F1, a neurotrophic protein, emerges as a key inducer of extensive neuronal differentiation in retinoblastoma cells. Notably, it exerts a potent inhibitory effect on angiogenesis. Distinguished by its unique conformational characteristics, Serpin F1 does not undergo the S (stressed) to R (relaxed) transition typical of active serpins, resulting in the absence of serine protease inhibitory activity. Furthermore, its interaction with PNPLA2 serves to stimulate the phospholipase A2 activity of PNPLA2, underscoring the multifaceted roles of Serpin F1 in cellular processes.

Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; Serpin F1; Stromal cell-derived factor 3.

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice.