protein

HGF Protein, Mouse (HEK293, His)

HY-P70561

2 μg;10 μg;50 μg;100 μg

40;100;300;480 USD

HGF Protein, Mouse (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg

40;100;300;480 USD

HGF Protein, a potent mitogen, stimulates mature hepatocyte cell growth and acts as a hepatotrophic factor for various tissues. As an activating ligand for MET receptor tyrosine kinase, HGF binds and promotes dimerization, activating MAPK signaling through TMPRSS13 cleavage. Structurally, HGF comprises alpha and beta chains connected by a disulfide bond. Interaction with SRPX2 enhances its mitogenic activity. HGF Protein, Mouse (HEK293, His) is the recombinant mouse-derived HGF protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

HGF protein is a potent mitogen that stimulates the growth of mature parenchymal hepatocyte cells and acts as a hepatotrophic factor for a wide range of tissues and cell types. It functions as an activating ligand for the receptor tyrosine kinase MET, binding to it and facilitating its dimerization. HGF also activates MAPK signaling through the cleavage and activation of TMPRSS13. Structurally, HGF is composed of an alpha chain and a beta chain joined by a disulfide bond. Additionally, it interacts with SRPX2, promoting increased mitogenic activity of HGF.

Hepatopoietin-A; Scatter factor; SF; deafness, autosomal recessive 39; DFNB39; F-TCF; hepatocyte growth factor; HGF

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.