protein

M-CSF Protein, Mouse (HEK293)

HY-P70553

2 μg;5 μg;10 μg;20 μg;50 μg;100 μg;500 μg

38;65;105;180;290;460;1350 USD

M-CSF Protein, Mouse (HEK293)

proteins

HEK293

2 μg;5 μg;10 μg;20 μg;50 μg;100 μg;500 μg

38;65;105;180;290;460;1350 USD

M-CSF Protein, Mouse (HEK293) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.

Mouse

Macrophage Colony Stimulating Factor (M-CSF) is a pro-inflammatory cytokine, constitutively produced by several cell types, such as fibroblasts, endothelial cells, stromal cells, macrophages, smooth muscle cells and osteoblasts, binds to its receptor CSF1R, and exists in several isoforms- as a secreted glycoprotein, a cell-surface protein and a proteoglycan [1] . M-CSF is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts, which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes seen in patients with rheumatoid arthritis [2] .

Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.