Noggin Protein, Human (CHO) | MedChem Express LLC HY-P7051A product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

Noggin Protein, Human (CHO)

catalog :

HY-P7051A

quantity :

2 μg;10 μg;50 μg

price :

45;120;460 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7051A

Product Name :

Noggin Protein, Human (CHO)

Product Type :

proteins

Host Species :

CHO

Size :

2 μg;10 μg;50 μg

List Price :

45;120;460 USD

list of Pubmed id :

375588512

Product Description :

Noggin Protein, Human (CHO) is an antagonist of bone morphogenetic proteins (BMPs), binds with high affinity to hBMP-4, and with lower affinity to hBMP-7; Noggin Protein is essential for proper skeletal development.

SpeciesSummary :

Human

Background :

Human Noggin protein has 205 amino acids (residues 28-232) after removal of its signal sequence (residues 1-27) and is secreted as a glycosylated, covalently linked homodimer, binds with high affinity to hBMP-4, and with lower affinity to hBMP-7 and acts as an antagonist of bone morphogenetic proteins (BMPs) [1] . Noggin is essential for proper skeletal development; excess BMP activity in the Noggin null mutant results in excess cartilage and failure to initiate joint formation [2] .

ALTnames :

rHuNoggin; NOG

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage