protein

M-CSF Protein, Human (CHO)

HY-P7050A

2 μg;10 μg;50 μg;100 μg

75;190;490;810 USD

M-CSF Protein, Human (CHO)

proteins

CHO

2 μg;10 μg;50 μg;100 μg

75;190;490;810 USD

375588511

M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

Human

Recombinant Human Macrophage Colony-stimulating Factor (CHO-expressed) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity [1] . Macrophage Colony Stimulating Factor (M-CSF) is a pro-inflammatory cytokine, constitutively produced by several cell types, such as fibroblasts, endothelial cells, stromal cells, macrophages, smooth muscle cells and osteoblasts, binds to its receptor CSF1R, and exists in several isoforms- as a secreted glycoprotein, a cell-surface protein and a proteoglycan [2] . M-CSF is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts, which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes seen in patients with rheumatoid arthritis [3] .

rHuM-CSF; CSF-1; MGI-IM

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.