protein

Transthyretin/TTR Protein, Human (127a.a, HEK293, His)

HY-P70500

10 μg;50 μg;100 μg

75;170;240 USD

Transthyretin/TTR Protein, Human (127a.a, HEK293, His)

proteins

HEK293

10 μg;50 μg;100 μg

75;170;240 USD

The transthyretin/TTR protein is a thyroid hormone binder that may be critical for transporting thyroxine from the bloodstream to the brain. Its structure is a homotetramer, forming a dimer of dimers, and its central channel is suggested to play a role in thyroxine binding and transport. Transthyretin/TTR Protein, Human (127a.a, HEK293, His) is the recombinant human-derived Transthyretin/TTR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Transthyretin/TTR Protein, Human (127a.a, HEK293, His) is 127 a.a., with molecular weight of (16-21) & (31-37) kDa, respectively.

Human

Transthyretin/TTR Protein serves as a thyroid hormone-binding protein, likely playing a crucial role in transporting thyroxine from the bloodstream to the brain. Forming a homotetramer, it is structured as a dimer of dimers, with subunits assembling around a central channel capable of accommodating two ligand molecules. This suggests a functional significance in the binding and transport of thyroxine. Additionally, Transthyretin/TTR Protein interacts with RBP4, highlighting potential cooperative actions in the regulation of thyroid hormone dynamics. The homotetrameric configuration and ligand-binding properties underscore the importance of Transthyretin/TTR in facilitating the transport and distribution of thyroid hormones, emphasizing its role in maintaining endocrine balance.

Transthyretin; ATTR; Prealbumin; TBPA; TTR; PALB

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0 or 20 mM PB, 150 mM NaCl, pH 7.8.

Room temperature in continental US; may vary elsewhere.