protein

M-CSF Protein, Human

HY-P7050

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

45;120;320;500;900;1350;2000 USD

M-CSF Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

45;120;320;500;900;1350;2000 USD

375588510

M-CSF Protein, Human is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

Human

Recombinant Human Macrophage Colony-stimulating Factor is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity [1] . Macrophage Colony Stimulating Factor (M-CSF) is a pro-inflammatory cytokine, constitutively produced by several cell types, such as fibroblasts, endothelial cells, stromal cells, macrophages, smooth muscle cells and osteoblasts, binds to its receptor CSF1R, and exists in several isoforms- as a secreted glycoprotein, a cell-surface protein and a proteoglycan [2] . M-CSF is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts, which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes seen in patients with rheumatoid arthritis [3] .

rHuM-CSF; CSF-1; MGI-IM

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of 50 mM Tris-HCl, pH 8.0 or 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.