protein

Osteopontin/OPN Protein, Human (HEK293, His)

HY-P70499

5 μg;10 μg;50 μg;100 μg

35;55;150;250 USD

Osteopontin/OPN Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;55;150;250 USD

Osteopontin/OPN Protein, a key non-collagenous bone protein, strongly binds to hydroxyapatite, contributing to the mineralized matrix. Its significant role in cell-matrix interactions is evident. Acting as a cytokine, OPN promotes interferon-gamma and interleukin-12 production while suppressing interleukin-10, crucial for type I immunity. Osteopontin/OPN Protein, Human (HEK293, His) is the recombinant human-derived Osteopontin/OPN protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Osteopontin/OPN Protein, Human (HEK293, His) is 298 a.a., with molecular weight of 50-65 kDa.

Human

Osteopontin (OPN) protein is a significant non-collagenous bone protein that exhibits a strong binding affinity to hydroxyapatite, making it an integral component of the mineralized matrix. It likely plays a crucial role in cell-matrix interactions. Moreover, OPN acts as a cytokine, facilitating the production of interferon-gamma and interleukin-12 while suppressing the production of interleukin-10. These functions are vital in the pathway that promotes type I immunity.

Osteopontin; Bone Sialoprotein 1; Nephropontin; Secreted Phosphoprotein 1; SPP-1; Urinary Stone Protein; Uropontin; SPP1; BNSP; OPN

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.