protein

Serpin F1 Protein, Human (HEK293, N-His)

HY-P70498A

5 μg;10 μg;50 μg;100 μg;500 μg

45;75;170;280;900 USD

Serpin F1 Protein, Human (HEK293, N-His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

45;75;170;280;900 USD

Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, N-His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of Serpin F1 Protein, Human (HEK293, N-His) is 399 a.a., with molecular weight of ~49.37 kDa.

Human

Neurotrophic protein Serpin F1 plays a pivotal role in promoting extensive neuronal differentiation in retinoblastoma cells. Additionally, it functions as a potent inhibitor of angiogenesis. Notably, Serpin F1 does not undergo the S (stressed) to R (relaxed) conformational transition typical of active serpins, resulting in the absence of serine protease inhibitory activity. Furthermore, it interacts with PNPLA2, fostering the phospholipase A2 activity of PNPLA2.

Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; Serpin F1; SERPINF1; PEDF

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.