protein

KGF-2/FGF-10 Protein, Human (169a.a)

HY-P7048

2 μg;5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;55;85;200;320;600;880;1250 USD

KGF-2/FGF-10 Protein, Human (169a.a)

proteins

E. coli

2 μg;5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

30;55;85;200;320;600;880;1250 USD

375588508

KGF-2/FGF-10 Protein, Human (169a.a) is a heparin-binding protein that binds to FGF2 IIIb and FGFR1III-b receptors, promotes the growth, proliferation, and differentiation of epithelial cells and can enhance corneal wound healing.

Human

Keratinocyte growth factor-2 (KGF-2), also called fibroblast growth factor-10 (FGF-10), is a soluble 170-amino-acid polypeptide secreted by fibroblasts and endothelial cells acting primarily on epithelial cells. Its functions mainly mediated by FGF-2 IIIb receptor, a transmembrane receptor, expressed exclusively by epithelial cells. KGF-2 promotes the growth, proliferation, and differentiation of epithelial cells, with promising effects in treating epithelial damage. KGF-2 enhances corneal wound healing in a rabbit model of carbon dioxide laser-induced corneal injury [1] . Keratinocyte growth factor-2 (KGF-2) is a 20-kD heparin-binding protein, and also binds to FGFR1III-b, which may explain the severely impaired lung development of FGF-10 null mice [2] .

rHuKGF-2/FGF-10; Fibroblast Growth Factor-10

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS or 20 mM PB, 150 mM NaCl, pH 7.4 or 10 mM Tris, 5% Sucrose, 4% Mannitol, 0.02% Tween 80, pH 8.0 or 50 mM Tris-HCL, 300 mM NaCL, pH 7.4 or PBS , pH 7.4, 5-8 % trehalose.

Room temperature in continental US; may vary elsewhere.