protein

IL-4 Protein, Human (His)

HY-P70445A

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

50;125;310;500;1400;2300 USD

IL-4 Protein, Human (His)

Protein

Human

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

50;125;310;500;1400;2300 USD

IL-4 Protein is an endogenous agonist of IL-4 receptor (IL-4R), which works through the JAK1/JAK3-STAT6 signaling pathway. It can cooperate with SCF to promote the proliferation of human intestinal mast cells (ED50=100 pg/mL) and enhance the release of mediators such as histamine mediated by IgE receptor. IL-4 Protein can inhibit the production of IL-8 by human monocytes and regulate the secretion of endothelial cell factors. It is mainly used for IL-4R targeted therapy research of tumors (such as malignant pleural mesothelioma) and allergic diseases. IL-4 Protein, Human is a recombinant protein of human IL-4, expressed by E. coli, with 6His tag at N-terminal.