protein

IL-33 Protein, Human

HY-P7041

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;125;350;595;1500;2400 USD

IL-33 Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

45;125;350;595;1500;2400 USD

375588498

IL-33 Protein, Human, a Th2 cytokine, is a specific ligand for ST2L.

Human

Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of Th2 cell related cytokines including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. The IL-33-ST2 signaling cascade plays some roles in the pathophysiology of chronic allergic conjunctivitis through the activation of mast cells [1] .

rHuIL-33; IL-1F11; NF-HEV; DVS 27

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or 20 mM PB, 150 mM NaCl, pH 7.4 or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.