protein

IGFBP-5 Protein, Mouse (HEK293, His)

HY-P70408

10 μg

120 USD

IGFBP-5 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg

120 USD

IGFBP-5 protein is a member of the IGFBP family that significantly prolongs the half-life of IGF and modulates its growth-promoting effects in cell culture. The multifunctional IGFBP-5 can inhibit or stimulate cellular responses to IGF by altering the kinetics of interaction with IGF receptors. IGFBP-5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGFBP-5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGFBP-5 Protein, Mouse (HEK293, His) is 252 a.a., with molecular weight of ~38.0 kDa.

Mouse

IGFBP-5 Protein, a member of the insulin-like growth factor-binding proteins (IGFBPs), assumes a crucial role in extending the half-life of insulin-like growth factors (IGFs) and modulating their growth-promoting effects on cell culture. Demonstrating versatility, IGFBP-5 has been shown to either inhibit or stimulate the cellular responses elicited by IGFs. This regulatory function is achieved by IGFBP-5 through its ability to alter the interaction dynamics between IGFs and their corresponding cell surface receptors. By exerting control over these molecular interactions, IGFBP-5 contributes to the intricate modulation of IGF signaling pathways, influencing cellular responses related to growth and development. The diverse effects of IGFBP-5 underscore its significance in the regulatory framework that governs the interplay between IGFs and their receptors.

rMuInsulin-like growth factor-binding protein 5/IGFBP5, His; BP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US;may vary elsewhere.