protein

IL-21 Protein, Human

HY-P7038

2 μg;10 μg;20 μg;50 μg;100 μg;500 μg

35;95;145;260;470;1320 USD

IL-21 Protein, Human

proteins

E. coli

2 μg;10 μg;20 μg;50 μg;100 μg;500 μg

35;95;145;260;470;1320 USD

375588493

IL-21 Protein, Human is a class 1 cytokine, which is produced by activated CD4 + T cells. IL-21 Protein stimulation of T cells, B cells and NK cells leads to enhanced proliferation and mature effector function.

Human

Interleukin-21 (IL-21) is a pleiotropic cytokine that has key functions in both the innate and adaptive immunity and the regulation of autoimmunity. IL-21 has a range of activities likely to potentiate antitumor immunoresponses. IL-21 has a role as a single agent in the treatment of melanoma. IL-21 also has significant activity against various types of cancer in combination with monoclonal antibodies or signaling inhibitors [1] . Recombinant human interleukin-21 (rIL-21), a human recombinant interleukin, with Cetuximab, a monoclonal antibody, targeting the epidermal growth factor receptor [2] .

rHuIL-21; Za11; IL21

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or 20 mM PB, 150 mM NaCl, pH 7.4 or PBS, pH 7.4, 5 % trehalose, 5 % mannitol and 0.01% Tween80.

Room temperature in continental US; may vary elsewhere.