product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
Glypican-1/GPC1 Protein, Human (HEK293, His)
catalog :
HY-P70343
quantity :
10 μg;50 μg
price :
90;250 USD
more info or order :
product information
Catalog Number :
HY-P70343
Product Name :
Glypican-1/GPC1 Protein, Human (HEK293, His)
Product Type :
proteins
Host Species :
HEK293
Size :
10 μg;50 μg
List Price :
90;250 USD
Product Description :
Glypican-1 (GPC1) is a heparan sulfate-containing cell surface proteoglycan. Glypican-1/GPC1 Protein, Human (HEK293, His) is the recombinant human-derived Glypican-1/GPC1 protein, expressed by HEK293 , with N-6*His labeled tag.
SpeciesSummary :
Human
Background :
Glypican-1 (GPC1) Protein is a cell surface proteoglycan characterized by its association with heparan sulfate. It binds alpha-4 (V) collagen through the heparan sulfate side chains and plays a role in Schwann cell myelination. Additionally, GPC1 may act as a catalyst in the conversion of prion protein PRPN(C) to PRNP(Sc) by associating with both forms of PRPN, targeting them to lipid rafts, and facilitating their interaction. Moreover, GPC1 is essential for proper skeletal muscle differentiation, as it sequesters FGF2 in lipid rafts, preventing its binding to receptors (FGFRs) and inhibiting FGF-mediated signaling.
ALTnames :
rHuGlypican-1/GPC1, His; Glypican-1; GPC1
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage :
Room temperature in continental US;may vary elsewhere.
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA