protein

MMP-12 Protein, Mouse (HEK293, His)

HY-P70342

10 μg;50 μg

143;400 USD

MMP-12 Protein, Mouse (HEK293, His)

proteins

HEK293

10 μg;50 μg

143;400 USD

MMP-12 protein has significant elastolytic activity and may contribute to tissue damage and remodeling.Its substrate preferences include preference for leucine at the P1' site and aromatic/hydrophobic residues at the P1 site, and preference for small hydrophobic residues such as alanine at the P3 site.MMP-12 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MMP-12 protein, expressed by HEK293 , with C-6*His labeled tag.

Mouse

The MMP-12 protein emerges as a potential contributor to tissue injury and remodeling, demonstrating significant elastolytic activity. Its versatility is reflected in its ability to accommodate both large and small amino acids at the P1' site, displaying a preference for leucine. Furthermore, MMP-12 exhibits specificity in substrate preferences, favoring aromatic or hydrophobic residues at the P1 site, with a preference for small hydrophobic residues, particularly alanine, at the P3 site. These characteristics underscore the intricate role of MMP-12 in the modulation of extracellular matrix components, suggesting its involvement in processes related to tissue remodeling and homeostasis.

rMuMacrophage metalloelastase/MMP12, His; Macrophage metalloelastase; MME; Matrix metalloproteinase-12; MMP-12; Mmp12; Mme; Mmel

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl,0.01%Tween80, 1 mM EDTA, 50% Glycerol, pH 6.0.

Shipping with dry ice.