protein

IL-15 Protein, Human

HY-P7034

2 μg;10 μg;50 μg;100 μg

55;145;350;560 USD

IL-15 Protein, Human

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

55;145;350;560 USD

375588488

IL-15 Protein, Human is a pleiotropic cytokine, including T, B and NK cell-stimulatory activities.

Human

Interleukin 15 is a cytokine that shares many biological properties with IL-2, including T, B and NK cell-stimulatory activities. Interleukin-15 has significant potential in cancer immunotherapy as an activator of antitumor CD8 T and natural killer (NK) cells [1] . Interleukin-15 (IL-15) is a pleiotropic cytokine and a member of the four α-helix bundle family of cytokines which include IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. IL-15 exhibits a broad biological activity and induces the differentiation and proliferation of T, B and natural killer (NK) cells. As a potent pro-inflammatory cytokine, IL-15 plays an important and complex role in autoimmune disease and inflammation. IL-15 plays a pivotal role in some hematological malignancies and presents anti-tumor effects. The direct administration of IL-15 has shown anti-tumor effects in several preclinical mouse tumor models [2] .

rHuIL-15; IL15

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or 20 mM PB, 150 mM NaCl, pH 7.0 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.