protein

Erythropoietin receptor/EpoR Protein, Human (HEK293, His)

HY-P70314

2 μg;10 μg;50 μg;100 μg

35;95;240;400 USD

Erythropoietin receptor/EpoR Protein, Human (HEK293, His)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg

35;95;240;400 USD

The EPOR Protein functions as a receptor for erythropoietin, mediating erythroblast proliferation and differentiation upon EPO stimulation. The heterodimer triggers the JAK2/STAT5 signaling cascade and, in certain cell types, activates STAT1, STAT3, and the LYN tyrosine kinase. Additionally, isoform EPOR-T acts as a dominant-negative receptor, modulating EPOR-mediated signaling pathways. Erythropoietin receptor/EpoR Protein, Human (HEK293, His) is the recombinant human-derived Erythropoietin receptor/EpoR protein, expressed by HEK293 , with C-6*His labeled tag.