protein

Fumarylacetoacetase/FAH Protein, Human (HEK293, His)

HY-P70307

5 μg;10 μg;50 μg;100 μg

85;135;350;560 USD

Fumarylacetoacetase/FAH Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

85;135;350;560 USD

Fumarylacetoacetase/FAH Protein is a key enzyme in the metabolism of phenylalanine and tyrosine expressed primarily in the liver. Deficiency of FAH causes hereditary tyrosinemia type 1. Fumarylacetoacetase/FAH Protein, Human (HEK293, His) is the recombinant human-derived Fumarylacetoacetase/FAH protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fumarylacetoacetase/FAH Protein, Human (HEK293, His) is 418 a.a., with molecular weight of ~43.0 kDa.

Human

Fumarylacetoacetase is an enzyme encoded by the FAH gene on human chromosome 15. The FAH gene is believed to be involved in the catabolism of phenylalanine in humans and is a key enzyme in the metabolism of phenylalanine and tyrosine, which is mainly expressed in the liver. FAH is a protein homodimer that splits the carbon-carbon bond of fumarylacetic acid in a hydrolysis reaction. The active site of FAH contained Ca 2+ . Deficiency of FAH causes hereditary tyrosinemia type 1 [1] [2] [3] .

rHuFumarylacetoacetase/FAH, His; Fumarylacetoacetase; FAA; Beta-Diketonase; Fumarylacetoacetate Hydrolase; FAH

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.5.

Room temperature in continental US; may vary elsewhere.