protein

Glucosamine (N-acetyl)-6-Sulfatase/GNS Protein, Human (HEK293, His)

HY-P70300

10 μg;50 μg

170;510 USD

Glucosamine (N-acetyl)-6-Sulfatase/GNS Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

170;510 USD

Glucosamine (N-acetyl)-6-Sulfatase/GNS Protein is a lysosomal enzyme present in all cells. It is involved in the catabolism of heparin, heparin sulfate and keratin sulfate. Deficiency of this enzyme leads to inadequate substrate accumulation and lysosomal storage impairment IIID mucopolysaccharidosis. Glucosamine (N-acetyl) -6-Sulfatase/GNS Protein, Human (HEK293, His) is the recombinant human-derived Glucosamine, expressed by HEK293 , with C-6*His labeled tag.

Human

Sulfatase catalyzes the hydrolysis of O- and N-sulfate esters from various substrates. Most sulfatases are found in lysosomes. Used to remove sulfate from glycosaminoglycans (GAGs), glycopeptides and glycolipids (GLs). N-acetylglucosamine-6-sulfatase is a lysosomal enzyme present in all cells. It is involved in the catabolism of heparin, heparin sulfate and keratin sulfate. Deficiency of this enzyme leads to inadequate substrate accumulation and lysosomal storage impairment IIID mucopolysaccharidosis [1] [2] [3] [4] .

rHuN-acetylglucosamine-6-sulfatase/GNS, His; N-Acetylglucosamine-6-Sulfatase; Glucosamine-6-Sulfatase; G6S; GNS

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.

Shipping with dry ice.