protein

IL-10 Protein, Human

HY-P7030

5 μg;20 μg;100 μg

100;300;820 USD

IL-10 Protein, Human

proteins

E. coli

5 μg;20 μg;100 μg

100;300;820 USD

375588482

IL-10 Protein, Human is an anti-inflammatory, immunomodulatory cytokine that regulates mucosal inflammation.

Human

Interleukin 10 (IL-10) is an anti-inflammatory, immunomodulatory cytokine that regulates mucosal inflammation. A promising alternative is interleukin 10 (IL-10), a cytokine with multiple anti-inflammatory and immunoregulatory activities, including inhibition of T-cell/macrophage activation and proinflammatory cytokine synthesis [1] . IL-10, a cytokine possessing strong anti-inflammatory properties, is under investigation for its therapeutic use as an immunosuppressant. The immunosuppressive actions of IL-10 and corticosteroids include inhibition of proinflammatory cytokine production by monocytes and polymorphonuclear leukocytes (IFN-γ, TNF-α, IL-1β, IL-6, GM-CSF) both at the protein and messenger RNA levels and prevention of mitogen-induced T-cell proliferation [2] .

rHuIL-10; CSIF

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against 20mM Tris, 20mM NaCl, pH 6.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization or PBS, pH 7.4, 5% Trehalose, 5% Mannitol.

Room temperature in continental US; may vary elsewhere.