protein

IL-1RA/IL-1RN Protein, Human

HY-P7029

5 μg;10 μg;50 μg;100 μg

50;80;160;220 USD

IL-1RA/IL-1RN Protein, Human

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

50;80;160;220 USD

375588480

IL-1RA/IL-1RN Protein, Human is a member of the IL-1 family that binds to IL-1 receptors.

Human

The production of Human Interleukin-1 Receptor Antagonist Protein (IL-1ra) is stimulated by many substances including adherent IgG, other cytokines, and bacterial or viral components. Endogenous IL-1Ra is produced in numerous experimental animal models of disease as well as in human autoimmune and chronic inflammatory diseases. Treatment of human diseases with recombinant human IL-1Ra shows an absence of benefit in sepsis syndrome [1] . IL-1 receptor antagonist (IL-1ra) has provided a tool for blocking IL-1 activity in vivo , leading to a detailed understanding of the role of this cytokine in the inflammatory response [2] .

rHuIL-1RA; IL-1RN; IRAP

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 8% Trehalose, 4% Mannitol, 50 mM NaCl, 0.05% Tween 80, pH 7.5 or 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

Room temperature in continental US; may vary elsewhere.