protein

MIF Protein, Human (N-His)

HY-P70288A

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;85;230;420;1200;2000 USD

MIF Protein, Human (N-His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;85;230;420;1200;2000 USD

The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (N-His) is the recombinant human-derived MIF protein, expressed by E. coli , with N-6*His labeled tag. The total length of MIF Protein, Human (N-His) is 115 a.a., with molecular weight of approximately 11.67 kDa.

Human

MIF Protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens. Its expression at sites of inflammation suggests its involvement in regulating macrophage function in host defense. MIF counteracts the anti-inflammatory effects of glucocorticoids. Although MIF has phenylpyruvate tautomerase and dopachrome tautomerase activity in vitro, the physiological substrate of MIF is still unknown. It remains unclear whether the tautomerase activity is relevant to its cytokine activity.

rHuMacrophage migration inhibitory factor/MIF, His; Macrophage migration inhibitory factor; MIF; MMIF; Glycosylation-inhibiting factor; GLIF; L-dopachrome tautomerase; Phenylpyruvate tautomerase

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.