protein

GDF-8 Protein, Human (His)

HY-P702842

20 μg;50 μg

148;280 USD

GDF-8 Protein, Human (His)

proteins

E. coli

20 μg;50 μg

148;280 USD

GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human (His) is the recombinant Human-derived GDF-8 protein, expressed by E. coli , with N-6*His.

Human

GDF-8 (Growth Differentiation Factor 8) serves as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and interacts with WFIKKN2, thereby inhibiting the activity of the latter. Additionally, GDF-8 interacts with FSTL3, contributing to its regulatory role in modulating skeletal muscle growth.

Growth/differentiation factor 8; GDF-8; Myostatin; MSTN

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0 or PBS, 6% Trehalose, pH 7.4.

Room temperature in continental US; may vary elsewhere.