protein

Myeloperoxidase/MPO Protein, Mouse (HEK293, His)

HY-P70282

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

60;95;250;400;750;1100;1750 USD

Myeloperoxidase/MPO Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;250 μg;500 μg;1 mg

60;95;250;400;750;1100;1750 USD

Myeloperoxidase (MPO) protein, integral to polymorphonuclear leukocytes' host defense system, catalyzes the production of hypohalous acids, notably hypochlorous acid, enhancing microbicidal activity.Beyond antimicrobial functions, MPO mediates the proteolytic cleavage of alpha-1-microglobulin, yielding t-alpha-1-microglobulin.This processed form inhibits low-density lipoprotein particle oxidation, contributing to vascular damage limitation.Myeloperoxidase/MPO Protein, Mouse (HEK293, His) is the recombinant mouse-derived Myeloperoxidase/MPO protein, expressed by HEK293 , with C-10*His labeled tag.

Mouse

Myeloperoxidase (MPO) protein plays a vital role in the host defense system of polymorphonuclear leukocytes, contributing to microbicidal activity against a diverse range of organisms. Upon stimulation of polymorphonuclear leukocytes, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid under physiological conditions, along with other toxic intermediates that significantly enhance microbicidal activity in these cells. Beyond its antimicrobial functions, MPO is involved in mediating the proteolytic cleavage of alpha-1-microglobulin, generating t-alpha-1-microglobulin. This processed form exhibits potent inhibitory effects on the oxidation of low-density lipoprotein particles, thereby contributing to the limitation of vascular damage.

rMuMyeloperoxidase/MPO, His; Myeloperoxidase; MPO

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

Room temperature in continental US; may vary elsewhere.