protein

FABP3 Protein, Human (His)

HY-P70256

10 μg;50 μg

115;320 USD

FABP3 Protein, Human (His)

proteins

E. coli

10 μg;50 μg

115;320 USD

FABP3 Protein, Human (His) is a recombinant FABP3 protein with a His-flag. FABP3 Protein is expressed in the skeletal muscle, heart, brain and brown adipose tissue [1] .

Human

Fatty acid binding proteins (FABPs) are intracellular proteins and exhibit high affinity for small lipophilic ligands. FABP-3 is expressed in the skeletal muscle, heart, brain and brown adipose tissue. And its expression in skeletal muscles is elevated on consumption of a high fat diet. The gene encoding it is localized on human chromosome 1p35. FABP3 is a newly introduced plasma marker of acute myocardial infarction (AMI). FABP3 is identified as a novel selective autophagy substrate of OPTN (optineurin, a macroautophagy/autophagy receptor, is found to play a pivotal role in selective autophagy, coupling autophagy with bone metabolism). FABP3 promotes adipogenesis and inhibits osteogenesis of MSCs. Knockdown of FABP3 alleviates bone loss in optn-/ - mice and aged mice [1] [2] .

rHuFatty acid-binding protein/FABP3, His; Fatty Acid-Binding Protein Heart; Fatty Acid-Binding Protein 3; Heart-Type Fatty Acid-Binding Protein; H-FABP; Mammary-Derived Growth Inhibitor; MDGIMuscle Fatty Acid-Binding Protein; M-FABP; FABP3; FABP11; MDGI

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 6.5.

Room temperature in continental US; may vary elsewhere.