protein

ULBP3 Protein, Human (HEK293, His)

HY-P702558

2 μg;10 μg;50 μg;100 μg;250 μg

58;150;390;620;1185 USD

ULBP3 Protein, Human (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;250 μg

58;150;390;620;1185 USD

The ULBP3 protein plays a key role in natural killer cell cytotoxicity and activates the KLRK1/NKG2D receptor. The interaction of ULBP3 highlights its importance in mediating cytotoxic responses. ULBP3 Protein, Human (HEK293, His) is the recombinant human-derived ULBP3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ULBP3 Protein, Human (HEK293, His) is 187 a.a., with molecular weight of ~59 kDa.

Human

The ULBP3 protein plays a pivotal role in natural killer cell cytotoxicity by functioning as a ligand that binds to and activates the KLRK1/NKG2D receptor. ULBP3 mediates the cytotoxic responses of natural killer cells. Through its binding affinity with KLRK1/NKG2D, ULBP3 facilitates the activation of this receptor, contributing to the recognition and targeting of cells marked for elimination. Importantly, ULBP3 does not exhibit binding to beta2-microglobulin, as indicated by similarities in its interaction profile. This insight into the binding characteristics of ULBP3 further delineates its role as a key player in immune responses, specifically in the orchestration of natural killer cell activity.

NKG2D ligand 3; RAET1N; UL16 binding protein 3; ULBP3; ULBP-3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 6.2, 8% trehalose.

Room temperature in continental US; may vary elsewhere.