protein

SLC30A8 Protein, Mouse (Cell-Free, His)

HY-P702442

20 μg;50 μg;100 μg

550;1100;1650 USD

SLC30A8 Protein, Mouse (Cell-Free, His)

proteins

E. coli Cell-free

20 μg;50 μg;100 μg

550;1100;1650 USD

SLC30A8 Protein, a proton-coupled zinc ion antiporter, crucially regulates insulin secretion. Serving as a mediator, SLC30A8 enables zinc entry into pancreatic beta cell secretory granules, maintaining the required zinc concentration. This process finely tunes insulin release dynamics, emphasizing SLC30A8's pivotal role in physiological insulin secretion control and glucose homeostasis. SLC30A8 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived SLC30A8 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of SLC30A8 Protein, Mouse (Cell-Free, His) is 367 a.a., with molecular weight of 43.0&86 kDa.

Mouse

SLC30A8 Protein, identified as a proton-coupled zinc ion antiporter, plays a pivotal role in the intricate regulation of insulin secretion. Functioning as a mediator, SLC30A8 facilitates the entry of zinc into the lumen of pancreatic beta cell secretory granules. This process is crucial for maintaining the appropriate zinc concentration within the granules, ultimately influencing the dynamics of insulin release. By participating in the transport of zinc, SLC30A8 contributes to the finely tuned orchestration of cellular events within pancreatic beta cells, highlighting its significance in the physiological control of insulin secretion and, consequently, glucose homeostasis.

Proton-coupled zinc antiporter SLC30A8; Solute carrier family 30 member 8; Zinc transporter 8; ZnT-8

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from 20 mM Tris-HCl, 0.15M NaCl, 0.05%BRIJ-78, 6% Trehalose, pH 8.0.

Room temperature in continental US; may vary elsewhere.